1. 15:00

   F

   Burnley

   Arsenal

   0 0

   0 0
2. 17:30

   F

   Tottenham

   Man City

   1. 

   2 0

   0 0

   		60' O. Zinchenko
   S. Bergwijn 63'	1 - 0
   Son Heung-Min 71'	2 - 0

1. 15:30

   F

   Cologne

   Fribourg

   4 1

   0 0

   S. Bornauw 29'	1 - 0
   J. Córdoba 55'	2 - 0
   K. Ehizibue 90+1'	3 - 0
   I. Jakobs 90+2'	4 - 0

2. 18:00

   F

   Paderborn

   1. 

   Wolfsbourg

   2 1

   4 2

   B. Zolinski 22'	1 - 0
   	1 - 1	26' R. Knoche
   G. Holtmann 33'
   	1 - 2	40' D. Ginczek
   	1 - 3	60' D. Ginczek
   S. Vasiliadis 72'	2 - 3
   	2 - 4	76' M. Arnold

1. 12:00

   F

   Leganes

   Real Sociedad

   2 0

   1 1

   	0 - 1	20' A. Isak
   K. Omeruo 49'	1 - 1
   Óscar Rodríguez 90+4'	2 - 1

2. 14:00

   F

   Eibar

   Betis

   1 1

   1 1

   	0 - 1	7' N. Fekir
   Fabián Orellana 15'	1 - 1

3. 16:00

   F

   Bilbao

   Getafe

   0 0

   2 1

   	0 - 1	36' D. Suárez
   	0 - 2	50' Jaime Mata

4. 18:30

   F

   Séville

   Alavés

   1 0

   1 0

   	0 - 1	70' Joselu
   L. Ocampos 77'	1 - 1

5. 18:30

   F

   Villarreal

   Osasuna

   3 1

   1 0

   Paco Alcácer 45+1'	1 - 0
   	1 - 1	48' Aridane Hernández
   Rubén Peña 54'	2 - 1
   Santi Cazorla 59'	3 - 1

6. 21:00

   F

   Barcelone

   Levante

   2 2

   1 0

   Ansu Fati 30'	1 - 0
   Ansu Fati 31'	2 - 0
   	2 - 1	90+2' Rúben Vezo

1. 12:30

   F

   Juventus

   Fiorentina

   3 1

   0 0

   Cristiano Ronaldo 40'	1 - 0
   Cristiano Ronaldo 80'	2 - 0
   M. de Ligt 90+1'	3 - 0

2. 15:00

   F

   Atalanta

   Genoa

   1. 

   2 2

   2 2

   R. Tolói 12'	1 - 0
   	1 - 1	19' D. Criscito
   	1 - 2	33' A. Sanabria
   J. Iličić 35'	2 - 2
   		82' V. Behrami

3. 15:00

   F

   Milan

   Hellas

   1. 

   1 1

   1 1

   	0 - 1	13' D. Faraoni
   H. Çalhanoğlu 29'	1 - 1
   		68' S. Amrabat

4. 15:00

   F

   Lazio

   SPAL

   5 4

   1 0

   C. Immobile 3'	1 - 0
   F. Caicedo 16'	2 - 0
   C. Immobile 29'	3 - 0
   F. Caicedo 38'	4 - 0
   B. Adekanye 58'	5 - 0
   	5 - 1	65' S. Missiroli

5. 18:00

   F

   Lecce

   Torino

   4 2

   0 0

   A. Deiola 11'	1 - 0
   A. Barák 19'	2 - 0
   F. Falco 64'	3 - 0
   G. Lapadula 78'	4 - 0

6. 20:45

   F

   Udinese

   Inter Milan

   0 0

   2 0

   	0 - 1	64' R. Lukaku
   	0 - 2	71' R. Lukaku

1. 14:30

   F

   Club Bruges

   Antwerp

   1 0

   0 0

   H. Vanaken 84'

   1 - 0

2. 18:00

   F

   Anderlecht

   Mouscron

   1 0

   0 0

   A. Colassin 70'

   1 - 0

3. 20:00

   F

   Zulte-Waregem

   Waasland-Beveren

   5 3

   0 0

   S. Berahino 16'	1 - 0
   D. De Fauw 21'	2 - 0
   J. Vossen 43'	3 - 0
   J. Vossen 65'	4 - 0
   G. Bruno 79'	5 - 0

1. 12:15

   F

   Willem II

   Heracles

   1 1

   0 0

   S. Holmén 26'

   1 - 0

2. 14:30

   F

   Fortuna

   Heerenveen

   2 1

   1 1

   	0 - 1	6' M. van Bergen
   F. Passlack 15'	1 - 1
   S. Botman 74'	2 - 1

3. 14:30

   F

   VVV

   Utrecht

   1 0

   1 0

   O. Darfalou 51'	1 - 0
   	1 - 1	81' S. Gustafson

4. 16:45

   F

   Ajax

   PSV

   1 1

   0 0

   Q. Promes 35'

   1 - 0

1. 16:00

   F

   Maritimo

   Desportivo Aves

   1 1

   2 1

   	0 - 1	18' Ricardo Mangas
   Rodrigo Pinho 37'	1 - 1
   	1 - 2	62' Reko Silva

2. 16:00

   F

   Gil Vicente

   Moreirense

   1 0

   5 2

   	0 - 1	5' Filipe Soares
   	0 - 2	21' Gabrielzinho
   	0 - 3	52' Fábio Abreu
   	0 - 4	68' Filipe Soares
   	0 - 5	77' Pedro Nuno
   Samuel Lino 80'	1 - 5

3. 18:30

   F

   Santa Clara

   Paços

   2 0

   1 0

   Guilherme Schettine 47'	1 - 0
   Guilherme Schettine 80'	2 - 0
   	2 - 1	90+1' Marco Baixinho

4. 18:30

   F

   Sporting Braga

   Sporting

   1 0

   0 0

   Trincão 76'

   1 - 0

5. 21:00

   F

   Boavista

   Vitoria Guimaraes

   2 1

   0 0

   Carraça 23'	1 - 0
   Heriberto Tavares 55'	2 - 0

1. 11:30

   F

   MKE Ankaragücü

   Kasimpasa SK

   1 0

   1 1

   	0 - 1	7' M. Thiam
   G. Rodrigues 50'	1 - 1

2. 14:00

   F

   Gaziantep FK

   Sivasspor

   5 3

   1 1

   A. Maxim 4'	1 - 0
   	1 - 1	31' Hakan Arslan
   M. Demir 39'	2 - 1
   A. Maxim 44'	3 - 1
   S. Diarra 78'	4 - 1
   K. Özer 86'	5 - 1

3. 14:00

   F

   Alanya

   1. 

   Yeni Malatya

   2 1

   1 0

   A. Bakasetas 45+1'	1 - 0
   P. Cissé 48'	2 - 0
   F. Nsakala 60'
   	2 - 1	90+4' I. Chebake

4. 17:00

   F

   Galatasaray

   Kayserispor

   4 2

   1 0

   A. Büyük 5'	1 - 0
   R. Donk 21'	2 - 0
   S. Féghouli 64'	3 - 0
   	3 - 1	69' M. Mešanović
   S. Féghouli 90+4'	4 - 1

Group A

1. 17:00

   F

   FCNDB

   Pyramids

   0 0

   1 0

   0 - 1

   59' J. Antwi

2. 20:00

   F

   Enugu Rangers International

   Masry

   1 1

   1 1

   	0 - 1	6' Mahmoud Wadi
   I. George 20'	1 - 1

Group B

1. 17:00

   F

   Wits University

   Djoliba

   0 0

   2 1

   	0 - 1	15' B. Sanogo
   	0 - 2	46' O. Camara

2. 17:00

   F

   Al-Nasr

   Horoya

   0 0

   2 1

   	0 - 1	11' B. Haba
   	0 - 2	76' D. Nikièma

Group C

1. 20:00

   F

   Berkane

   Zanaco

   1 1

   1 1

   A. Traoré 2'	1 - 0
   	1 - 1	39' I. Dayo

2. 20:00

   F

   Motema Pembe

   ESAE

   1 1

   0 0

   V. Bongonga 3'

   1 - 0

Group D

1. 17:00

   F

   San-Pédro

   Enyimba

   2 2

   5 3

   	0 - 1	2' A. Bashir
   	0 - 2	3' V. Mbaoma
   S. Jimoh 6'	1 - 2
   	1 - 3	25' A. Oladapo
   I. Zan Bi 44'	2 - 3
   	2 - 4	75' V. Mbaoma
   	2 - 5	85' S. Dimgba

2. 17:00

   F

   HUSA

   Paradou AC

   0 0

   3 1

   	0 - 1	10' O. Kismoun
   	0 - 2	72' O. Kismoun
   	0 - 3	90+5' Y. Bouzok