1. 15:00

   F

   Everton

   Wolverhampton

   1. 

   3 2

   2 1

   Richarlison 5'	1 - 0
   	1 - 1	9' R. Saïss
   A. Iwobi 12'	2 - 1
   	2 - 2	75' R. Jiménez
   Richarlison 80'	3 - 2
   		90+5' W. Boly

2. 17:30

   F

   Arsenal

   Tottenham

   2 1

   2 2

   	0 - 1	10' C. Eriksen
   	0 - 2	40' H. Kane
   A. Lacazette 45+1'	1 - 2
   P. Aubameyang 71'	2 - 2

Group G

1. 12:00

   F

   Kazakhstan

   Serbie

   0 0

   3 0

   	0 - 1	57' M. Mijatović
   	0 - 2	81' A. Poljak
   	0 - 3	83' T. Matić

1. 15:30

   F

   Brême

   Augsbourg

   1. 

   3 2

   2 1

   Y. Osako 6'	1 - 0
   	1 - 1	12' R. Vargas
   J. Sargent 21'	2 - 1
   		34' S. Lichtsteiner
   	2 - 2	46' R. Vargas
   Y. Osako 67'	3 - 2

2. 18:00

   F

   Francfort

   Düsseldorf

   2 0

   1 1

   	0 - 1	36' R. Hennings
   B. Dost 57'	1 - 1
   Gonçalo Paciência 86'	2 - 1

1. 17:00

   F

   Valence

   Majorque

   2 1

   0 0

   Dani Parejo 43'	1 - 0
   Dani Parejo 57'	2 - 0

2. 19:00

   F

   Atlético

   Eibar

   3 1

   2 2

   	0 - 1	7' Charles
   	0 - 2	19' Anaitz Arbilla
   João Félix 27'	1 - 2
   Vitolo 52'	2 - 2
   T. Partey 90'	3 - 2

3. 19:00

   F

   Espanyol

   Grenade

   0 0

   3 1

   	0 - 1	13' Antonio Puertas
   	0 - 2	68' Carlos Fernández
   	0 - 3	74' R. Azeez

4. 21:00

   F

   Villarreal

   Real Madrid

   1. 

   2 1

   2 1

   Gerard Moreno 12'	1 - 0
   	1 - 1	45+1' G. Bale
   Moi Gómez 74'	2 - 1
   	2 - 2	86' G. Bale
   		90+4' G. Bale

1. 18:00

   F

   Lazio

   Rome

   1 0

   1 1

   	0 - 1	17' A. Kolarov
   Luis Alberto 58'	1 - 1

2. 20:45

   F

   Atalanta

   Torino

   2 1

   3 1

   	0 - 1	24' K. Bonifazi
   D. Zapata 38'	1 - 1
   D. Zapata 54'	2 - 1
   	2 - 2	57' Álex Berenguer
   	2 - 3	66' A. Izzo

3. 20:45

   F

   Cagliari

   Inter Milan

   1 0

   2 1

   	0 - 1	27' L. Martínez
   JP Galvão 50'	1 - 1
   	1 - 2	72' R. Lukaku

4. 20:45

   F

   Genoa

   Fiorentina

   2 1

   1 0

   C. Zapata 11'	1 - 0
   C. Kouamé 65'	2 - 0
   	2 - 1	76' E. Pulgar

5. 20:45

   F

   Lecce

   Hellas

   0 0

   1 0

   0 - 1

   81' M. Pessina

6. 20:45

   F

   Sassuolo

   Sampdoria

   1. 

   4 3

   1 0

   D. Berardi 29'	1 - 0
   D. Berardi 36'	2 - 0
   D. Berardi 43'	3 - 0
   		45+1' R. Vieira
   H. Traorè 47'	4 - 0
   	4 - 1	67' F. Quagliarella

7. 20:45

   F

   Udinese

   Parme

   1 1

   3 1

   K. Lasagna 17'	1 - 0
   	1 - 1	43' Y. Gervinho
   	1 - 2	59' R. Gagliolo
   	1 - 3	75' R. Inglese

1. 14:30

   F

   Club Bruges

   Genk

   1 1

   1 0

   S. Deli 41'	1 - 0
   	1 - 1	67' B. Heynen

2. 18:00

   F

   Anderlecht

   Standard de Liège

   1 1

   0 0

   A. Saelemaekers 31'

   1 - 0

3. 20:00

   F

   Zulte-Waregem

   Antwerp

   2 2

   0 0

   S. Berahino 35'	1 - 0
   D. De Fauw 44'	2 - 0

4. 20:00

   F

   La Gantoise

   Cercle Bruges

   3 3

   2 1

   L. Depoitre 11'	1 - 0
   	1 - 1	15' S. Peeters
   J. David 24'	2 - 1
   J. David 27'	3 - 1
   	3 - 2	90+2' S. Peeters

1. 12:15

   F

   Twente

   Utrecht

   1. 

   3 1

   1 0

   Aitor Cantalapiedra 22'	1 - 0
   	1 - 1	59' Adrián Dalmau
   H. Vučkić 68'	2 - 1
   		90+3' L. Guwara
   Aitor Cantalapiedra 90+3'	3 - 1

2. 14:30

   F

   Sparta

   Ajax

   1 0

   4 2

   	0 - 1	25' Q. Promes
   	0 - 2	31' H. Ziyech
   	0 - 3	58' D. Tadić
   	0 - 4	60' H. Ziyech
   H. Dervişoğlu 75'	1 - 4

3. 16:45

   F

   Willem II

   Feyenoord

   0 0

   1 0

   0 - 1

   74' S. Berghuis

4. 16:45

   F

   Vitesse

   AZ

   2 1

   1 1

   	0 - 1	33' T. Koopmeiners
   T. Matavž 45+1'	1 - 1
   M. Bero 90+6'	2 - 1

5. 20:00

   F

   Waalwijk

   PSV

   1 1

   3 0

   M. Meulensteen 43'	1 - 0
   	1 - 1	65' P. Quasten
   	1 - 2	76' T. Baumgartl
   	1 - 3	78' K. Mitroglou

1. 17:00

   F

   Tondela

   1. 

   Santa Clara

   0 0

   0 0

   F. Moufi 25'

2. 19:30

   F

   Porto

   Vitoria Guimaraes

   1. 
   2. 

   3 1

   0 0

   		1' E. Tapsoba
   M. Marega 14'	1 - 0
   		78' Davidson
   Iván Marcano 88'	2 - 0
   M. Marega 90+3'	3 - 0

3. 22:00

   F

   Sporting Braga

   Benfica

   0 0

   4 1

   	0 - 1	25' Pizzi
   	0 - 2	47' Pizzi
   	0 - 3	51' Bruno Viana
   	0 - 4	73' Ricardo Esgaio

1. 13:00

   F

   Ural

   Krasnodar

   2 1

   4 2

   	0 - 1	19' D. Skopintsev
   Y. Bavin 21'	1 - 1
   	1 - 2	38' Ari
   O. El Kabir 68'	2 - 2
   	2 - 3	80' D. Utkin
   	2 - 4	82' Wanderson

2. 15:30

   F

   Arsenal

   CSKA

   1 1

   2 1

   D. Lesovoy 10'	1 - 0
   	1 - 1	17' I. Akhmetov
   	1 - 2	74' C. Gogoua

3. 18:00

   F

   Spartak

   Zénith

   0 0

   1 1

   0 - 1

   41' Y. Zhirkov

1. 18:15

   F

   Genclerbirligi SK

   Basaksehir

   1 1

   2 0

   G. Sio 36'	1 - 0
   	1 - 1	83' D. Ba
   	1 - 2	90' E. Višća

2. 18:15

   F

   Sivasspor

   Gaziantep FK

   1 0

   1 1

   	0 - 1	35' P. Twumasi
   A. Koné 72'	1 - 1

3. 20:45

   F

   Fenerbahce

   Trabzon

   1 1

   1 1

   Garry Rodrigues 17'	1 - 0
   	1 - 1	27' C. Ekuban

4. 20:45

   F

   Yeni Malatya

   Alanya

   2 0

   3 3

   	0 - 1	20' C. Gülselam
   	0 - 2	22' J. Fernándes
   	0 - 3	44' P. Cissé
   T. Bifouma 47'	1 - 3
   A. Jahović 57'	2 - 3